Cookies Policy
NOTEDFIRST SEEN 2026-08-13 · VERSION 20260813_rev01 · COMPARED WITH 20260812_rev01
What changed, in plain language
Nothing about your cookies changed. The only difference is that the scrambled codes in the "email protection" links for HubSpot and Cloudflare contact addresses were regenerated — these codes are randomized every time the page loads. The cookie names, providers, categories, storage times, and purposes are all identical.
This change appears to be cosmetic (formatting, typos, or contact details).
Changelog
- ± CHANGEDContact-email link codes regenerated
PLOS hides the HubSpot and Cloudflare contact email addresses behind Cloudflare's email-protection scrambler. Those scrambled codes get a fresh random value each time the page is generated, so the links look different but point to the same addresses. No cookie was added, removed, or changed.
https://plos.org/cdn-cgi/l/email-protection#a1d1d3c8d7c0c2d8e1c9d4c3d2d1ced58fc2cecc
https://plos.org/cdn-cgi/l/email-protection#1c6c6e756a7d7f655c74697e6f6c7368327f7371
Full text changes — 20260812_rev01 to 20260813_rev01
COLOUR MARKS THE SEVERITY OF A FLAGGED CLAUSE · + AND − MARK ADDED AND REMOVED
| 35 | 35 | | \_cer.v | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | Up to 31 Days | Tracks whether a visitor has visited the site before. | |
| 36 | 36 | | \_ce.s | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | 1 Year | Tracks a recording visitor session unique ID, host, and start time. | |
| 37 | 37 | | \_ce.cch | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | 1 Second | Used to check if cookies can be added. | |
| 38 | 38 | | \_ce.gtld | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | 1 Second | Used to identify the top-level domain. | |
| 39 | 39 | | ce\_need\_secure\_cookie | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | 1 Second | Used to determine cookie security parameters. | |
| 40 | 40 | | ce\_successful\_csp\_check | Crazy Egg, 16220 Ridgeview Ln La Mirada, CA 90638, USA [Privacy Policy](https://www.crazyegg.com/privacy) | Performance and Analytics | 24 Hours | Determines if the page has a Content Security Policy rule that would prevent tracking. | |
| 41 | | \_\_hs\_opt\_out | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#a1d1d3c8d7c0c2d8e1c9d4c3d2d1ced58fc2cecc) | Necessary | 6 month | This cookie is used by the opt-in privacy policy to remember not to ask the visitor to accept cookies again. | | |
| 42 | | \_\_hs\_do\_not\_track | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#dfafadb6a9bebca69fb7aabdacafb0abf1bcb0b2) | Necessary | 6 month | This cookie can be set to prevent the tracking code from sending any information to HubSpot. | | |
| 43 | | \_\_hs\_initial\_opt\_in | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#cebebca7b8afadb78ea6bbacbdbea1bae0ada1a3) | Necessary | 7 days | This cookie is used to prevent the banner from always displaying when visitors are browsing in strict mode. | | |
| 44 | | \_\_hs\_cookie\_cat\_pref | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#3b4b49524d5a58427b534e59484b544f15585456) | Necessary | 6 months | This cookie is used to record the categories a visitor consented to. | | |
| 45 | | \_\_hs\_gpc\_banner\_dismiss | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#4f3f3d26392e2c360f273a2d3c3f203b612c2022) | Necessary | 180 days | This cookie is used when the Global Privacy Control banner is dismissed. | | |
| 46 | | \_\_hs\_notify\_banner\_dismiss | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#ddadafb4abbcbea49db5a8bfaeadb2a9f3beb2b0) | Necessary | 180 days | This cookie is used when the website uses a Notify consent banner type. | | |
| 47 | | hs\_ab\_test | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#6b1b19021d0a08122b031e09181b041f45080406) | Necessary | End of the session | This cookie is used to consistently serve visitors the same version of an A/B test page they've seen before. | | |
| 48 | | \_key | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#cabab8a3bcaba9b38aa2bfa8b9baa5bee4a9a5a7) | Necessary | 14 days | When visiting a password-protected page, this cookie is set so future visits to the page from the same browser do not require login again. | | |
| 49 | | \_\_hsmem | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA[\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#7a0a08130c1b19033a120f18090a150e54191517) | Necessary | 7 days | This cookie is set when visitors log in to a HubSpot-hosted site. It contains encrypted data that identifies the membership user when they are currently logged in. | | |
| 50 | | hs-membership-csrf | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#c5b5b7acb3a4a6bc85adb0a7b6b5aab1eba6aaa8) | Necessary | End of the session | This cookie is used to ensure that content membership logins cannot be forged. | | |
| 41 | | \_\_hs\_opt\_out | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#1c6c6e756a7d7f655c74697e6f6c7368327f7371) | Necessary | 6 month | This cookie is used by the opt-in privacy policy to remember not to ask the visitor to accept cookies again. | | |
| 42 | | \_\_hs\_do\_not\_track | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#cdbdbfa4bbacaeb48da5b8afbebda2b9e3aea2a0) | Necessary | 6 month | This cookie can be set to prevent the tracking code from sending any information to HubSpot. | | |
| 43 | | \_\_hs\_initial\_opt\_in | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#48383a213e292b3108203d2a3b38273c662b2725) | Necessary | 7 days | This cookie is used to prevent the banner from always displaying when visitors are browsing in strict mode. | | |
| 44 | | \_\_hs\_cookie\_cat\_pref | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#e9999b809f888a90a9819c8b9a99869dc78a8684) | Necessary | 6 months | This cookie is used to record the categories a visitor consented to. | | |
| 45 | | \_\_hs\_gpc\_banner\_dismiss | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#93e3e1fae5f2f0ead3fbe6f1e0e3fce7bdf0fcfe) | Necessary | 180 days | This cookie is used when the Global Privacy Control banner is dismissed. | | |
| 46 | | \_\_hs\_notify\_banner\_dismiss | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#c5b5b7acb3a4a6bc85adb0a7b6b5aab1eba6aaa8) | Necessary | 180 days | This cookie is used when the website uses a Notify consent banner type. | | |
| 47 | | hs\_ab\_test | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#e797958e9186849ea78f928594978893c984888a) | Necessary | End of the session | This cookie is used to consistently serve visitors the same version of an A/B test page they've seen before. | | |
| 48 | | \_key | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#7a0a08130c1b19033a120f18090a150e54191517) | Necessary | 14 days | When visiting a password-protected page, this cookie is set so future visits to the page from the same browser do not require login again. | | |
| 49 | | \_\_hsmem | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA[\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#2e5e5c47584f4d576e465b4c5d5e415a004d4143) | Necessary | 7 days | This cookie is set when visitors log in to a HubSpot-hosted site. It contains encrypted data that identifies the membership user when they are currently logged in. | | |
| 50 | | hs-membership-csrf | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#bacac8d3ccdbd9c3fad2cfd8c9cad5ce94d9d5d7) | Necessary | End of the session | This cookie is used to ensure that content membership logins cannot be forged. | | |
| 51 | 51 | | \_\_cfruid | |
| 52 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#7b0b09120d1a18023b130e19080b140f55181416) | |
| 52 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#bacac8d3ccdbd9c3fad2cfd8c9cad5ce94d9d5d7) | |
| 53 | 53 | |
| 54 | 54 | Cloudflare, Inc. 101 Townsend St. San Francisco, CA 94107 |
| 55 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#1276627d52717e7d6776747e7360773c717d7f) | |
| 55 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#95f1e5fad5f6f9fae0f1f3f9f4e7f0bbf6faf8) | |
| 56 | 56 | |
| 57 | 57 | | Necessay | End of the session | This cookie is set by HubSpot's CDN provider because of their rate limiting policies. Learn more about Cloudflare cookies. | |
| 58 | 58 | | \_\_cfuvid | |
| 59 | 59 | |
| 60 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#b6c6c4dfc0d7d5cff6dec3d4c5c6d9c298d5d9db) | |
| 60 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#fa8a88938c9b9983ba928f98898a958ed4999597) | |
| 61 | 61 | |
| 62 | 62 | Cloudflare, Inc. 101 Townsend St. San Francisco, CA 94107 |
| 63 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#9ffbeff0dffcf3f0eafbf9f3feedfab1fcf0f2) | |
| 63 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#c7a3b7a887a4aba8b2a3a1aba6b5a2e9a4a8aa) | |
| 64 | 64 | |
| 65 | 65 | | Necessay | End of the session | This cookie is set by HubSpot's CDN provider because of their rate limiting policies. Learn more about Cloudflare cookies. | |
| 66 | 66 | | \_\_cf\_bm | |
| 67 | 67 | |
| 68 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#18686a716e797b6158706d7a6b68776c367b7775) | |
| 68 | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#5f2f2d36293e3c261f372a3d2c2f302b713c3032) | |
| 69 | 69 | |
| 70 | 70 | Cloudflare, Inc. 101 Townsend St. San Francisco, CA 94107 |
| 71 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#e286928da2818e8d9786848e839087cc818d8f) | |
| 71 | [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#2642564966454a495342404a4754430845494b) | |
| 72 | 72 | |
| 73 | 73 | | Necessary | 30 minutes | This cookie is set by HubSpot's CDN provider and is a necessary cookie for bot protection. Learn more about Cloudflare cookies. | |
| 74 | | \_\_hstc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#b5c5c7dcc3d4d6ccf5ddc0d7c6c5dac19bd6dad8) | Performance and analytics | 6 months | The main cookie for tracking visitors. | | |
| 75 | | hubspotutk | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#89f9fbe0ffe8eaf0c9e1fcebfaf9e6fda7eae6e4) | Performance and analytics | 6 months | This cookie keeps track of a visitor's identity. It is passed to HubSpot on form submission and used when deduplicating contacts. | | |
| 76 | | \_\_hssc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#6f1f1d06190e0c162f071a0d1c1f001b410c0002) | Performance and analytics | 6 months | This cookie keeps track of sessions. | | |
| 77 | | \_\_hssrc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#8afaf8e3fcebe9f3cae2ffe8f9fae5fea4e9e5e7) | Performance and analytics | End of the session | Whenever HubSpot changes the session cookie, this cookie is also set to determine if the visitor has restarted their browser | | |
| 74 | | \_\_hstc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#bfcfcdd6c9dedcc6ffd7caddcccfd0cb91dcd0d2) | Performance and analytics | 6 months | The main cookie for tracking visitors. | | |
| 75 | | hubspotutk | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#cbbbb9a2bdaaa8b28ba3bea9b8bba4bfe5a8a4a6) | Performance and analytics | 6 months | This cookie keeps track of a visitor's identity. It is passed to HubSpot on form submission and used when deduplicating contacts. | | |
| 76 | | \_\_hssc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#8bfbf9e2fdeae8f2cbe3fee9f8fbe4ffa5e8e4e6) | Performance and analytics | 6 months | This cookie keeps track of sessions. | | |
| 77 | | \_\_hssrc | HubSpot, Inc. Two Canal Park, Cambridge, MA 02141 USA [\[email protected\]](https://plos.org/cdn-cgi/l/email-protection#95e5e7fce3f4f6ecd5fde0f7e6e5fae1bbf6faf8) | Performance and analytics | End of the session | Whenever HubSpot changes the session cookie, this cookie is also set to determine if the visitor has restarted their browser | |